cholesterol acyltransferase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T23521	VULM 1457		Acyltransferase
	VULM 1457 is a potent ACAT inhibitor. VULM 1457 has remarkable hypolipidaemic activity and improves the overall myocardial ischaemia-reperfusion injury outcomes. VULM1457 significantly reduces production and secretion of...		Acyltransferase
T23550	YM-750	YM 750	Acyltransferase
	YM-750 is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with an IC50 value of 0.18 μM. ACAT is an enzyme that catalyzes the conversion of cholesterol and long-chain fatty-acyl-coenzyme A into cholest...		Acyltransferase
T8314	RP-64477	RP64477	Acyltransferase
	RP-64477 is the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT) inhibitor.		Acyltransferase
T25651	Lecimibide	DuP128,DuP-128,DuP 128	Acyltransferase
	Lecimibide (DuP 128) is a potent and selective inhibitor of acyl coenzyme A: cholesterol acyltransferase (ACAT), which can be used to study diseases due to high lipids.		Acyltransferase
T27245L	Eflucimibe	L0081,F-12511	Acyltransferase
	Eflucimibe (L0081) is an acyl coenzyme A: cholesterol acyltransferase inhibitor for the treatment of cardiovascular disease and endocrine and metabolic disorders, and can be used to study atherosclerosis and hyperlipidem...		Acyltransferase
T2753	Avasimibe	PD-148515,CI-1011	P450 , Acyltransferase
	Avasimibe (PD-148515) is an orally bioavailable inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT, IC50: 3.3 μM) that prevents cholesterol deposition in the arterial wall. It also inhibits human P450 isoenz...		P450 , Acyltransferase
T36126	TMP-153
	Acyl-CoA:cholesterol acyltransferase (ACAT) catalyses the esterification of excess cellular cholesterol with fatty acids and is important for intestinal cholesterol absorption, hepatic lipoprotein secretion, and choleste...
T70575	AS 183
	AS 183 is an inhibitor of cholesterol acyltransferase (ACAT).
T15187	E-5324		Others
	E-5324 is potent cholesterol acyltransferase (ACAT) inhibitor (IC50s: 44 to 190 nM).		Others
T28820	SMP-797 HCl	SMP-797,SMP 797,SMP797
	SMP-797 HCl, an ACAT (acyl-CoA-cholesterol acyltransferase) inhibitor, is used potentially for the treatment of Hyperlipidemia.
T24117	Guineesine	Pipyahyine
	Guineesine is an Acyl-CoA. It acts by inhibiting cholesterol acyltransferase.
T40553	ACAT-IN-6
	ACAT-IN-6, an acyl-Coenzyme A: cholesterol acyltransferase (ACAT) inhibitor, displays potent inhibition of NF-κB mediated transcription.
T26548	Acaterin
	Acaterin, an inhibitor of acyl-CoA: cholesterol acyltransferase (ACAT), inhibits synthesis of cholesteryl ester in macrophage J774.
T39415	ACAT-IN-9
	ACAT-IN-9, acts as an inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT). By doing so, it effectively suppresses NF-κB mediated transcription.
T70300	Avasimibe sodium
	Avasimibe sodium is an acyl coenzyme A: cholesterol acyltransferase (ACAT) inhibitor.
T39414	ACAT-IN-7
	ACAT-IN-7 is a compound that acts as an inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT) enzyme. It effectively suppresses the transcription process mediated by NF-κB.
T13678	Enniatin A
	Enniatin A, a Fusarium mycotoxin, inhibits acyl-CoA: cholesterol acyltransferase (ACAT) with an IC50 of 22 μM in rat liver microsome enzyme assays.
T39417	ACAT-IN-2
	ACAT-IN-2 is a potent inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT). This compound effectively blocks NF-κB mediated transcription.
T40551	ACAT-IN-3
	ACAT-IN-3, a potent inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT), effectively suppresses NF-κB dependent transcription.
T40552	ACAT-IN-10
	ACAT-IN-10 is an acyl-Coenzyme A: cholesterol acyltransferase (ACAT) inhibitor. It inhibits NF-κB mediated transcription with a weak activity.